News

JOM Lab joins two CZI Pediatric Networks!
September 2021
The Ordovas-Montanes lab will participate in two CZI Pediatrics Networks focused on generating single-cell atlases from healthy children. Jose will serve as coordinating PI on a project to generate a global pediatric cell atlas of nasal and oral mucosa where the team hopes to understand the single-cell biology of the nasal mucosa in children living in several cities in the United States, the Bahamas, The Gambia, Bangladesh, and India. The lab is supporting a project coordinated by Jay Thiagarajah to map the early childhood gut across ancestry, geography and environment with groups in the United States and Pakistan. Read more about the CZI Pediatric Networks here.

Welcome Jaclyn!
August 2021
Welcome Jaclyn, who has joined the lab as a PhD student from the department of immunology, co-advised with Dr. Arlene Sharpe! Jaclyn will study how tissue metabolism influences T cells in infectious and inflammatory diseases.

Sam is awarded the Cancer Research Institute Irvington Postdoctoral Fellowship!
June 2021
Sam Kazer, our first postdoc in the lab, was awarded a Cancer Research Institute Irvington Postdoctoral Fellowship for his proposed work to study trained immunity and inflammatory memory in respiratory viral infections! Read more about the award here.

Jose is named a Pew Scholar in the Biomedical Sciences!
June 2021
Jose was named a Pew Scholar in the Biomedical Sciences, where he joins 21 other Pew Scholars within their cohort. This provides support for all lab members to explore how different cells within a tissue contribute to the initiation and propagation of an inflammatory response. Read more about the award here.

Amanda is awarded the NSF-GRFP fellowship!
March 2021
Amanda Hornick, our first PhD student in the lab, was awarded the NSF-GRFP fellowship! Congratulations Amanda!!

JOM Lab and friends receive a grant from the Helmsley Charitable Trust!
March 2021
The Ordovas-Montanes lab together with Jeffrey Moffitt, Leslie Kean, and Scott Snapper were awarded a grant from the Helmsley Charitable Trust to chart molecular and spatial single-cell remodeling in pediatric Crohn’s disease. This effort is part of the Gut Cell Atlas. Read more about the award here.

Welcome Ginny!
February 2021
Welcome Ginny, who has joined the lab as a postdoc! She previously earned her PhD in the lab of Robert Welner at the University of Alabama at Birmingham.

Happy New Year!
January 1, 2021
Happy new year! From the Ordovas-Montanes lab to you, we hope that the new year is one filled with love, compassion, good food, and exciting science.

Jose is named a NYSCF - Robertson Investigator!
October 20, 2020
The New York Stem Cell Foundation (NYSCF) has announced its 2020 class of NYSCF - Robertson Investigators, and Jose is one of them! This award provides our lab critical funding over five years, allowing us to carry out our work. Way to go, Jose! Read more about the award here.

Peter, Andrew, and Josh join the lab!
September 2020
Peter, Andrew, and Josh have officially joined our lab for their PhDs. We are so excited (and lucky) to have them!

Study Describing ACE2 as an Interferon-Stimulated Gene Out in Cell
April 21, 2020
Our study showing ACE2, the entry receptor for SARS-CoV-2, as an interferon-stimulated gene is now out in Cell here. Datasets analyzed in this study are described here and can be downloaded from our single-cell portal here. We hope these data prove invaluable in the global fight against the COVID-19 pandemic.

Pre-print on ACE2 as an Interferon-Stimulated Gene available now on bioRxiv
March 18, 2020
Our pre-print work detailing ACE2 upregulation in response to interferons, and type I interferons in particular, is now available here. Descriptions of the datasets analyzed in the study as well as the data can be found on our COVID-19 Resource page.

COVID-19 resources, data now available under Resources
March 14, 2020
In light of the spread of SARS-CoV-2, we are sharing multiple scRNA-seq datasets across both health and disease that harbor cells expressing ACE2 (the gene encoding the host receptor) and TMPRSS2 (the gene involved in processing the viral spike protein). We are sharing these resources for SARS-CoV-2 on the Alexandria Project. This is a project focused on enabling the community to explore single-cell data of relevance to infectious disease. An overview and introduction to the datasets can be found on our website here. We hope these data will be a useful resource for the community. We thank our colleagues for their willingness to share unpublished data, the study participants and donors, and the clinicians and scientists alike on the front lines of this pandemic.

The lab's first review is out!
February 3, 2020
The lab's first review is out now in Nature Reviews Immunology, titled "Distribution and storage of inflammatory memory in barrier tissue". We discuss what that means in terms of factors like cell state, cell lineage, and environmental exposure. Take a look here!
Thanks to our co-authors from the Rakoff-Nahoum and Shalek labs for helping us see this review to the finish line!